Physics of Genome Organization: Phase Separation

FOCUS · Q06 · ID: 46218

Presentations

  • ORAL · Invited

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    Publication: Lee, D.S.W., Wingreen, N.S. & Brangwynne, C.P. Chromatin mechanics dictates subdiffusion and coarsening dynamics of embedded condensates. Nat. Phys. 17, 531–538 https://doi.org/10.1038/s41567-020-01125-8 Jan 11 (2021)

    Zhang Y, Lee DSW, Meir Y, Brangwynne CP, Wingreen NS. Mechanical frustration of phase separation In the cell nucleus by chromatin. Phys Rev Lett. Jun 25;126(25):258102. Doi: 10.1103/Physrevlett.126.258102. PMID: 34241518. (2021)

    Presenters

    • Ned S Wingreen

      • Princeton University

    Authors

    • Ned S Wingreen

      • Princeton University

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  • ORAL

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    Publication: Currently, we are working on two manuscripts which will be posted to biorxiv soon. One focuses on the theoretical and analytical aspects of the model, while the other looks at its application to the organization of constitutive heterochromatin.

    Presenters

    • Ramin Basir

      • University of Pennsylvania

    Authors

    • Ramin Basir

      • University of Pennsylvania

    • Vivek b Shenoy

      • University of Pennsylvania

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  • ORAL

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    Publication: [1] A liquid state perspective on dynamics of chromatin compartments, R. Laghmach, M. Di Pierro and D. A. Potoyan, Submitted to Frontiers Biophysics
    [2] The interplay of chromatin phase separation and lamina interactions in nuclear organization, R. Laghmach, M. Di Pierro and D. A. Potoyan, Biophysical Journal (2021) https://doi.org/10.1016/j.bpj.2021.10.012
    [3] Mesoscale liquid model of chromatin recapitulates nuclear order of eukaryotes, R. Laghmach, M. Di Pierro and D. A. Potoyan, Biophysical Journal, 0006-3495 (2020) https://doi.org/10.1016/j.bpj.2019.09.013

    Presenters

    • Rabia Laghmach

      • Iowa State University

    Authors

    • Rabia Laghmach

      • Iowa State University

    • Michele Di Pierro

      • Northeastern University

    • Davit Potoyan

      • Iowa State University

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  • ORAL

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    Presenters

    • Jan-Hendrik Spille

      • University of Illinois at Chicago

    Authors

    • Jan-Hendrik Spille

      • University of Illinois at Chicago

    • Ganesh Pandey

      • Department of Physics, University of Illinois at Chicago

    • Aishwarya Katiki

      • Department of Physics, University of Illinois at Chicago

    • Saurabh Priyadarshi

      • Department of Microbiology and Immunology, University of Illinois at Chicago

    • Filmon Medhanie

      • Department of Physics, University of Illinois at Chicago

    • Amy L Kenter

      • Department of Microbiology and Immunology, University of Illinois at Chicago

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  • ORAL

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    Presenters

    • Kaustubh Wagh

      • University of Maryland, College Park/Laboratory of Receptor Biology and Gene Expression, NIH

    Authors

    • Kaustubh Wagh

      • University of Maryland, College Park/Laboratory of Receptor Biology and Gene Expression, NIH

    • Rikke AM Jensen

      • Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense

    • R. Louis Schiltz

      • Laboratory of Receptor Biology and Gene Expression, NCI, NIH

    • Ville Paakinaho

      • Institute of Biomedicine, University of Eastern Finland, Kuopio

    • Susanne Mandrup

      • Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense

    • Diego M Presman

      • Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), CONICET-Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Buenos Aires

    • Arpita Upadhyaya

      • University of Maryland, College Park

    • Gordon L Hager

      • Laboratory of Receptor Biology and Gene Expression, NIH

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  • ORAL

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    Presenters

    • Janni Harju

      • Vrije Universiteit Amsterdam

    Authors

    • Janni Harju

      • Vrije Universiteit Amsterdam

    • Anna Meijering

      • Vrije Universiteit Amsterdam

    • Kata Sarlós

      • University of Copenhagen

    • Christian F Nielsen

      • University of Copenhagen

    • Hannes Witt

      • Vrije Universiteit Amsterdam

    • Emma Kerklingh

      • Vrije Universiteit Amsterdam

    • Guus H Haasnoot

      • Vrije Universiteit Amsterdam

    • Anna H Bizard

      • University of Copenhagen

    • Iddo Heller

      • Vrije Universiteit Amsterdam

    • Ying Liu

      • University of Copenhagen

    • Erwin Peterman

      • Vrije Universiteit Amsterdam

    • Ian D Jackson

      • University of Copenhagen

    • Gijs Wuite

      • Vrije Universiteit Amsterdam

    • Chase P Broedersz

      • Department of Physics and Astronomy, Vrije Universiteit Amsterdam, Netherlands & Arnold-Sommerfeld-Center for Theoretical Physics and Center for NanoScience, LMU, Germany
      • Vrije Universiteit Amsterdam

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  • ORAL

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    Presenters

    • Rakesh Das

      • Mechanobiology Institute, National University of Singapore, Singapore 117411

    Authors

    • Rakesh Das

      • Mechanobiology Institute, National University of Singapore, Singapore 117411

    • Takahiro Sakaue

      • Department of Physical Sciences, Aoyama Gakuin University, 5-10-1 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5258, JAPAN

    • G. V. Shivashankar

      • Paul Scherrer Institute, Villigen, Switzerland

    • Jacques Prost

      • Laboratoire de Physique Statistique
      • Laboratoire Physico Chimie Curie, Institut Curie, Paris Sciences Lettres Research University, CNRS UMR168, 75005 Paris, France

    • Tetsuya Hiraiwa

      • Mechanobiology Institute, National University of Singapore, Singapore 117411

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