Perturbing polymerization and nucleation of RAD51 recombinase in a stochastic lattice model

POSTER

Abstract

RAD51 plays a crucial role in the homologous recombination process. We have developed a stochastic Monte Carlo lattice model to study how perturbing different binding properties of RAD51 affects the polymerization of RAD51-RAD51 and its mutants in solution and the nucleation of RAD51 polymers on a single-stranded DNA.

*University of Iowa FUTURE in BioMedecine ProgramIOWA NSF EPSCor GrantUniversity of Nothern Iowa Capacity Building Grant

Presenters

  • Ali S Tabei

    • University of Northern Iowa

Authors

  • Ali S Tabei

    • University of Northern Iowa

  • Sabryn Labenz

    • University of Northern Iowa

  • Blaine Williams

    • University of Northern Iowa

  • Jenna Heinen

    • University of Northern Iowa