Mechanics of Cells and Tissues II

Presentations

• Active response of metabolically intact isolated nuclei to compression

  ORAL

  March 6, 2024, 8:00 AM – March 6, 2024, 8:12 AM

  Presenters

  • Paul A Janmey

    • University of Pennsylvania

  Authors

  • Fitzroy J Byfield

    • University of Pennsylvania

  • Alison E Patteson

    • Syracuse University

  • Paul A Janmey

    • University of Pennsylvania

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• Complex Rheology in Single Cells: compression stiffening but shear softening

  ORAL

  March 6, 2024, 8:12 AM – March 6, 2024, 8:24 AM

  Publication: Actin and vimentin: equal partners in cell mechanics (manuscript in preparation)
  Single cells compression stiffen but shear soften (manuscript in preparation)

  Presenters

  • James P Conboy

    • Delft University of Technology

  Authors

  • James P Conboy

    • Delft University of Technology

  • Pouyan E Boukany

    • Delft University of Technology

  • Gijsje H Koenderink

    • Delft University of Technology

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• Stoichiometric Model for the Microtubule-mediated dynamics of centrosome and nucleus

  ORAL

  March 6, 2024, 8:24 AM – March 6, 2024, 8:36 AM

  Presenters

  • Yuan-Nan Young

    • New Jersey Institute of Technology

  Authors

  • Yuan-Nan Young

    • New Jersey Institute of Technology

  • Reza Farhadifar

    • Flatiron Institute

  • Michael J Shelley

    • Flatiron Institute (Simons Foundation)

  • Justin Maramuthal

    • New Jersey Institute of Technology

  • Libin Liu

    • Flatiron Institute

  • Alex Barnett

    • Flatiron Institute

  View abstract →

• In situ single-cell mechanics of mouse preimplantation embryos

  ORAL

  March 6, 2024, 8:36 AM – March 6, 2024, 8:48 AM

  Presenters

  • Haiqian Yang

    • Massachusetts Institute of Technology MIT

  Authors

  • Haiqian Yang

    • Massachusetts Institute of Technology MIT

  • Ehsan Habibi

    • Broad Institute of MIT and Harvard

  • Anubhav Sinha

    • Broad Institute of MIT and Harvard

  • Aviv Regev

    • Broad Institute of MIT and Harvard

  • Fei Chen

    • Broad Institute of MIT and Harvard

  • Ming Guo

    • Massachusetts Institute of Technology MIT
    • MIT

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• On the Topology and Dynamics of Breast Cancer Cell Morphologies

  ORAL

  March 6, 2024, 8:48 AM – March 6, 2024, 9:00 AM

  Presenters

  • Christian Cunningham

    • Oregon State University

  Authors

  • Christian Cunningham

    • Oregon State University

  • Bo Sun

    • Oregon State University

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• Cancer Cell Footprinting and Exploration in Micropatterned Fibrinogen Mazes

  ORAL

  March 6, 2024, 9:00 AM – March 6, 2024, 9:12 AM

  Presenters

  • Trevor Reid

    • Oregon State University

  Authors

  • Trevor Reid

    • Oregon State University

  • Bo Sun

    • Oregon State University

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• Deciphering Tumor Heterogeneity in Triple-Negative Breast Cancer: The Crucial Role of Dynamic Cell-Cell and Cell-Matrix Interactions

  ORAL · Invited

  March 6, 2024, 9:12 AM – March 6, 2024, 9:48 AM

  Publication: Rare populations of invasive cells drive progression of heterogeneous tumors
  Leggett SE*, Brennan MC*, Martinez S,Tien J, Nelson CM. (under revision) 2023
  
  
  Mechanophenotyping of 3D multicellular clusters using displacement arrays of rendered tractions.
  Leggett SE, Patel M, Valentin TM, Gamboa L, Khoo AS, Williams EK, Franck C, Wong IY. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):5655-5663.

  Presenters

  • Susan Leggett

    • University of Illinois Urbana-Champaign

  Authors

  • Susan Leggett

    • University of Illinois Urbana-Champaign

  • Ian Wong

    • Brown University

  • Celeste Nelson

    • Princeton University

  • Molly Brennan

    • Princeton University

  • Mohak Patel

    • Google (Bard)

  • Christian Franck

    • University of Wisconsin - Madison

  • Sophia Martinez

    • Princeton University

  • Joe Tien

    • Boston University

  • Lena Gamboa

    • Port Therapeutics

  • Thomas Valentin

    • CSEM

  • Amanda Khoo

    • Mediar Therapeutics

  • Evelyn K Williams

    • Georgia Institute of Technology

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• Fluidization of jammed epithelia by noninvasive carcinoma in a heterogeneous tumor model.

  ORAL

  March 6, 2024, 9:48 AM – March 6, 2024, 10:00 AM

  Presenters

  • Karen Yu

    • Columbia University

  Authors

  • Karen Yu

    • Columbia University

  • Alex Devanny

    • Columbia University

  • Laura Kaufman

    • Columbia Univ
    • Columbia University

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• Modeling Nonlinear Dynamics of Cells in Confinement

  ORAL

  March 6, 2024, 10:00 AM – March 6, 2024, 10:12 AM

  Presenters

  • Pedrom Zadeh

    • Johns Hopkins University

  Authors

  • Pedrom Zadeh

    • Johns Hopkins University

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• Long-Wavelength Interface Fluctuations Between Different Cell Populations are Suppressed by Friction

  ORAL

  March 6, 2024, 10:12 AM – March 6, 2024, 10:24 AM

  Presenters

  • Haicen Yue

    • University of Vermont

  Authors

  • Haicen Yue

    • University of Vermont

  • Daniel M Sussman

    • Emory University

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• Model of cell-cell adhesions as cytockeleton-to-cytoskeleton linkers

  ORAL

  March 6, 2024, 10:24 AM – March 6, 2024, 10:36 AM

  Publication: None

  Presenters

  • XinXin Du

    • Simons Foundation Flatiron Institute

  Authors

  • XinXin Du

    • Simons Foundation Flatiron Institute

  • Michael J Shelley

    • Flatiron Institute (Simons Foundation)

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• Microrheology of suspended cells using optical traps

  ORAL

  March 6, 2024, 10:36 AM – March 6, 2024, 10:48 AM

  Presenters

  • Mingru Li

    • Duke University

  Authors

  • Mingru Li

    • Duke University

  • Paul A Janmey

    • University of Pennsylvania

  • Siyan He

    • Duke University

  • Brenton D Hoffman

    • Duke University

  • Fitzroy J Byfield

    • University of Pennsylvania

  • Christoph F Schmidt

    • Duke University

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• Combinatorial role of mechano-chemical cues in cell mechanics and state transitions

  ORAL

  March 6, 2024, 10:48 AM – March 6, 2024, 11:00 AM

  Presenters

  • M Sreepadmanabh

    • National Centre for Biological Sciences
    • National Centre for Biological Sciences-TIFR

  Authors

  • M Sreepadmanabh

    • National Centre for Biological Sciences
    • National Centre for Biological Sciences-TIFR

  • Ashitha B Arun

    • National Center for Biological Sciences

  • Nandhu K Babu

    • National Centre for Biological Sciences

  • Nivedita Chaudhary

    • Institute for Stem Cell Science and Regenerative Medicine

  • Dasaradhi Palakodeti

    • Institute for Stem Cell Science and Regenerative Medicine

  • Tapomoy Bhattacharjee

    • Tata Institute of Fundamental Research - NCBS
    • National Centre for Biological Sciences
    • National Centre for Biological Sciences-TIFR

  View abstract →