Molecular Machines II
FOCUS · Q08 · ID: 1107048
Presentations
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Millisecond Functional Dynamics of RNA Polymerases Elucidated by Markov State Models
ORAL · Invited
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Publication: 1. Unarta, I.S., Cao, S., Kubo, S., Wang, W., Cheung, P.P.H., Gao, X., Takada, S., Huang, X., "Role of Bacterial RNA Polymerase Gate Opening Dynamics in DNA Loading and Antibiotics Inhibition Elucidated by quasi-Markov State Model", Proc. Nat. Acad. Sci. U.S.A., 118(17), e2024324118, (2021)
2. Tse K.M., Xu, J., Xu, L., Sheong, F.K., Wang, S., Chow, H.Y., Gao, X., Li, X., Cheung, P.P., Wang, D.*, Zhang, Y., Huang, X., "Intrinsic Cleavage of RNA Polymerase II Adopts a Nucleobase-independent Mechanism Assisted by Transcript Phosphate", Nature Catalysis, 2, 228-235, (2019)
3. Da, L., Pardo, F. , Xu, L., Silva, D. , Zhang, L. , Gao, X., Wang, D., Huang, X., "Bridge Helix Bending Promotes RNA Polymerase II Backtracking Through a Critical and Conserved Threonine Residue", Nature Communications, 7, 11244, (2016)Presenters
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Xuhui Huang
- University of Wisconsin-Madison
Authors
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Xuhui Huang
- University of Wisconsin-Madison
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Speed variations of bacterial replisomes
ORAL
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Publication: Bhat, D., Hauf, S., Plessy, C., Yokobayashi, Y. and Pigolotti, S., 2022. Speed variations of bacterial replisomes. Elife, 11, p.e75884.
Presenters
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Simone Pigolotti
- Okinawa Institute of Science & Technolog
Authors
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Simone Pigolotti
- Okinawa Institute of Science & Technolog
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Deepak Bhat
- Okinawa Institute of Science & Technology
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Samuel Hauf
- Okinawa Institute of Science and Technology
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Charles Plessy
- Okinawa Institute of Science and Technology
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Yohei Yokobayashi
- Okinawa Institute of Science and Technology
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Bacterial replication initiation as precision control in biology
ORAL
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Presenters
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Haochen Fu
- UC San Diego
Authors
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Haochen Fu
- UC San Diego
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Dongyang Li
- University of California, San Diego
- Caltech
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Fangzhou Xiao
- Caltech
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Suckjoon Jun
- University of California, San Diego
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DBIO Thesis Prize Winner: Jonathon L. YulyElectron bifurcation and correlations in biological energy transduction
ORAL · Invited
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Publication: Yuly, J. L., Zhang, P., Lubner, C. E., Peters, J. W., & Beratan, D. N. (2020). Proceedings of the National Academy of Sciences, 117(35), 21045-21051.
Yuly, J. L., Zhang, P., Ru, X., Terai, K., Singh, N., & Beratan, D. N. (2021). Chem, 7(7), 1870-1886.
Yuly, J.L., Zhang, P., and Beratan, D.N. (2021). Current Opinion in Electrochemistry, 29, 100767.
Terai, K., Yuly, J.L., Zhang, P., and Beratan, D.N. (2022). Proceedings of the National Academy of Sciences, Submitted.
Presenters
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Jonathon L Yuly
- Princeton University
Authors
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Jonathon L Yuly
- Princeton University
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Peng Zhang
- Duke University
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Kiriko Terai
- Duke University
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David N Beratan
- Duke University
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A free-energy profile study of a bipedal single-stranded DNA nanowalker's walking gaits
ORAL
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Presenters
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Too Hon Lin
- National University of Singapore
Authors
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Too Hon Lin
- National University of Singapore
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How do self-assembled virus-like particles break open to expose their cargo?
ORAL
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Presenters
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Amelia W Paine
- Harvard University
Authors
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Amelia W Paine
- Harvard University
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Camila Cersosimo
- University of Rhode Island
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Vinothan N Manoharan
- Harvard University
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Speedy synthetic DNA motors are on a roll
ORAL · Invited
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Publication: "Chemical-to-mechanical molecular computation using DNA-based motors with onboard logic" Selma Piranej, Alisina Bazrafshan & Khalid Salaita; Nature Nanotechnology volume 17, pages514–523 (2022)
"Adhesive Dynamics Simulations of Highly Polyvalent DNA Motors" Aaron T. Blanchard, Selma Piranej, Victor Pan, and Khalid Salaita J. Phys. Chem. B 2022, 126, 39, 7495–7509
"DNA Gold Nanoparticle Motors Demonstrate Processive Motion with Bursts of Speed Up to 50 nm Per Second"Alisina Bazrafshan, Maria-Eleni Kyriazi, Brandon Alexander Holt, Wenxiao Deng, Selma Piranej, Hanquan Su, Yuesong Hu, Afaf H. El-Sagheer, Tom Brown, Gabriel A. Kwong, Antonios G. Kanaras, and Khalid Salaita, ACS Nano, vol. 15 (5), pg. 8427–8438Presenters
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Khalid Salaita
- Emory University
Authors
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Khalid Salaita
- Emory University
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Selma Piranej
- Emory University
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Mechanical Properties of BiP (Binding Immunoglobin Protein)
ORAL
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Presenters
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Zahra Alavi
- Loyola Marymount University
Authors
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Zahra Alavi
- Loyola Marymount University
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