DNA Mechanics and Gene Expression II

Presentations

• Torsional Mechanics of Fundamental Processes

  ORAL · Invited

  March 8, 2023, 8:00 AM – March 8, 2023, 8:36 AM

  Publication: 1. T. T. Le, M. Wu, J.H. Lee, N. Bhatt, J.T. Inman, J.M. Berger, and M. D. Wang. "Etoposide Promotes DNA Loop Trapping and Barrier Formation by Topoisomerase II." Nat Chem. Bio., under revision.
  2. X. Gao, Y. Hong, F. Ye, J.T. Inman, and M.D. Wang. "Torsional Stiffness of Extended and Plectonemic DNA." Phys. Rev. Lett. 127:028101 (2021).
  3. T.T. Le, X. Gao, S. Park, J. Lee, J. T. Inman, J.H. Lee, J.L. Killian, R.P. Badman, J.M. Berger, and M.D. Wang. "Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity." Cell 179: 619–631 (2019).

  Presenters

  • Michelle D Wang

    • Cornell University

  Authors

  • Michelle D Wang

    • Cornell University

  View abstract →

• Physical Mechanisms for DNA Twist Changes and Supercoiling Induced by Salt and Temperature Changes

  ORAL

  March 8, 2023, 8:36 AM – March 8, 2023, 8:48 AM

  Publication: Chen Zhang, Fujia Tian, Ying Lu, Bing Yuan, Zhi-Jie Tan, Xing-Hua Zhang*, and Liang Dai*. "Twist-diameter coupling drives DNA twist changes with salt and temperature", Science Advances 8, eabn1384 (2022).
  
  Xiao-Wei Qiang, Chen Zhang, Hai-Long Dong, Fu-Jia Tian, Hang Fu, Ya-Jun Yang, Liang Dai*, Xing-Hua Zhang*, and Zhi-Jie Tan*. "Multivalent cations reverse the twist-stretch coupling of RNA", Physical Review Letters 128, 108103 (2022).

  Presenters

  • Liang Dai

    • City Univ of Hong Kong

  Authors

  • Liang Dai

    • City Univ of Hong Kong

  View abstract →

• Tensile force in a single-stranded DNA gap

  ORAL

  March 8, 2023, 8:48 AM – March 8, 2023, 9:00 AM

  Presenters

  • Harold D Kim

    • Georgia Institute of Technology

  Authors

  • Harold D Kim

    • Georgia Institute of Technology

  View abstract →

• Detecting Poloidal Bias In DNA Minicircles

  ORAL

  March 8, 2023, 9:00 AM – March 8, 2023, 9:12 AM

  Presenters

  • Tony Lemos

    • Georgia Institute of Technology

  Authors

  • Tony Lemos

    • Georgia Institute of Technology

  View abstract →

• Stability of DNA double helix under sharp bending

  ORAL

  March 8, 2023, 9:12 AM – March 8, 2023, 9:24 AM

  Publication: 1. Stability diagram of small DNA minicircles, M. Kim, J. S. Kim, submitted
  2. Sequence-dependent twist-bend coupling in DNA minicircles, M. Kim, S. Bae, I. Oh, J. Yoo, J. S. Kim, Nanoscale, 13, 20186 (2021)

  Presenters

  • Jun Soo Kim

    • Ewha Womans University

  Authors

  • Jun Soo Kim

    • Ewha Womans University

  View abstract →

• Multiscale modeling of chromatin: from fibers to genes to chromosomes

  ORAL · Invited

  March 8, 2023, 9:24 AM – March 8, 2023, 10:00 AM

  Presenters

  • Tamar Schlick

    • New York University

  Authors

  • Tamar Schlick

    • New York University

  • Zilong Li

    • New York University

  • Zilong Li

    • New York University

  View abstract →

• Understanding Transcriptional Regulation by Characterizing Gene Regulatory Functions of Synthetic Loci in Mammalian Cells

  ORAL

  March 8, 2023, 10:00 AM – March 8, 2023, 10:12 AM

  Presenters

  • Zheng Diao

    • Rice University

  Authors

  • Zheng Diao

    • Rice University

  • Oleg A Igoshin

    • Rice Univ

  • Caleb J Bashor

    • Rice University

  View abstract →

• A Differentiable Model of Nucleic Acid Dynamics

  ORAL

  March 8, 2023, 10:12 AM – March 8, 2023, 10:24 AM

  Presenters

  • Ryan Krueger

    • Harvard University

  Authors

  • Ryan Krueger

    • Harvard University

  • Megan C Engel

    • University of Calgary
    • Harvard University

  • Michael P Brenner

    • Harvard University

  View abstract →

• Structural and Dynamic signatures of active chromatin polymers

  ORAL

  March 8, 2023, 10:24 AM – March 8, 2023, 10:36 AM

  Presenters

  • Sumitabha Brahmachari

    • Rice University

  Authors

  • Sumitabha Brahmachari

    • Rice University

  • Tomer Markovich

    • Rice University

  • Frederick C MacKintosh

    • Rice University

  • Jose N Onuchic

    • Rice University

  View abstract →