Brain Organoids: From morphogenesis to metamaterials

INVITED · A13 · ID: 783455

Presentations

  • ORAL · Invited

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    Publication: * S. Tong, R. Sknepnek, and A. Kosmrlj, "Linear viscoelastic response of the vertex model with internal and external dissipation: normal modes analysis", arXiv:2202.03261 (2022)
    * S. Tong, N. K. Singh, R. Sknepnek, and A. Kosmrlj, "Linear viscoelastic properties of the vertex model for epithelial tissues", PLoS Computational Biology 18, e1010135 (2022)

    Presenters

    • Andrej Kosmrlj

      • Princeton
      • Princeton University

    Authors

    • Andrej Kosmrlj

      • Princeton
      • Princeton University

    • Sijie Tong

      • Princeton University

    • Rastko Sknepnek

      • University of Dundee

    View abstract →

  • ORAL · Invited

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    Publication: 1. Watanabe M, Buth JE, Vishlaghi N, de la Torre-Ubeita L, Taxidis J, Khakh B, Coppola G, Pearson C, Yamauchi K, Gong D, Dai X, Damoiseaux R, Aliyari R, Liebscher S, Schenke-Layland K, Caneda C, Huang EJ, Zhang Y, Cheng G, Geschwind DH, Golshani P, Sun R, and Novitch BG. Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection. 2017. Cell Reports, 21(2):517-532

    2. Li C, Deng YQ, Wang S, Ma F, Aliyari R, Huang XY, Zhang NN, Watanabe M, Dong HL, Liu P, Li ZF, Ye Z, Tian M, Hong, S, Fan J, Zhao H, Li L, Vishlaghi N, Au C, Liu Y, Lu N, Du P, Qin FXF, Zhang B, Novitch BG, Xu Z, Qin CF, and Cheng G. 25-Hydroxycholesterol protects host against ZIKV infection and its associated mirocephaly. 2017. Immunity, 46(3):1-11.

    3. Samarasinghe RA, Miranda OA, Buth JE, Mitchell S, Ferando I, Watanabe M, Allison TF, Kurdian A, Gandal MJ, Golshani P, Plath K, Lowry WE, Parent JM, Mody I, and Novitch BG. Identification of neural oscillations and epileptic changes in human brain organoids. 2021. Nat Neurosci, 24(10):1488-1500.

    4. Watanabe M, Haney J, Vishlaghi N, Turcios F, Buth JE, Gu W, Collier AJ, Miranda OA, Chen D,
    Clark A, Plath K, Gandal M, and Novitch BG. TGF? superfamily signaling regulates the state of human pluripotency and competency to create telencephalic organoids. 2022. Stem Cell Reports, 17(10):2220-2238.

    Presenters

    • Momoko Watanabe

      • University of California, Irvine

    Authors

    • Momoko Watanabe

      • University of California, Irvine

    • Jessie E Buth

      • University of California, Los Angeles

    • Neda Vishlaghi

      • University of California, Los Angeles

    • Felix Turcios

      • University of California, Los Angeles

    • Ranmal A Samarasinghe

      • University of California, Los Angeles

    • Bennett G Novitch

      • University of California, Los Angeles

    View abstract →

  • ORAL · Invited

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    Publication: Maayan Karlinski, Irit Sagi, Amnon Buxboim, Orly Reiner (in preparation). ECM changes and Mechanical Properties of LIS1-/+ Brain Organoids.

    Aditya Kshirsagar, Anna Gorelik, Tsviya Olender, Tamar Sapir, Daisuke Tsuboi, Irit Rosenhek-Goldian, Sergey Malitsky, Maxim Itkin, Amir Argoetti, Yael Mandel-Gutfreund, Sidney R. Cohen, Jacob Hanna, Igor Ulitsky, Kozo Kaibuchi, Orly Reiner. LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways. bioRxiv 2022.03.08.483407; doi: https://doi.org/10.1101/2022.03.08.483407

    Karzbrun E, Kshirsagar A, Cohen SR, Hanna JH, Reiner O. Human Brain Organoids on a Chip Reveal the Physics of Folding. Nat Phys. 2018 May;14(5):515-522. doi: 10.1038/s41567-018-0046-7. Epub 2018 Feb 19. PubMed PMID: 29760764; PubMed Central PMCID: PMC5947782

    Presenters

    • Orly Reiner

      • Weizmann Institute of Science

    Authors

    • Orly Reiner

      • Weizmann Institute of Science

    View abstract →

  • ORAL · Invited

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    Presenters

    • J. M Schwarz

      • Syracuse University
      • Department of Physics and BioInspired Institute, Syracuse University, Syracuse, NY 13244, USA

    Authors

    • J. M Schwarz

      • Syracuse University
      • Department of Physics and BioInspired Institute, Syracuse University, Syracuse, NY 13244, USA

    View abstract →