Physics of Genome Organization: From DNA to Chromatin

Presentations

• Chromatin network retards droplet coalescence

  ORAL · Invited

  March 17, 2022, 3:00 PM – March 17, 2022, 3:36 PM

  Publication: doi: https://doi.org/10.1101/2021.03.02.433564

  Presenters

  • Bin Zhang

    • Massachusetts Institute of Technology MI
    • MIT

  Authors

  • Bin Zhang

    • Massachusetts Institute of Technology MI
    • MIT

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• Rheological Properties of Chromatin and Nuclear Microenvironment in Living Cells

  ORAL

  March 17, 2022, 3:36 PM – March 17, 2022, 3:48 PM

  Publication: [1] Ma et al. "Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow" Nature biotechnology 34 (5), 528-530.
  [2] Ma et al. "CRISPR-Sirius: RNA scaffolds for signal amplification in genome imaging" Nature methods 15 (11), 928-931.

  Presenters

  • Yu-Chieh Chung

    • The Ohio State University

  Authors

  • Yu-Chieh Chung

    • The Ohio State University

  • Madhoolika Bisht

    • The Ohio State University

  • Li-Chun Tu

    • The Ohio State University

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• Active Dynamics of Chromosome Polymers

  ORAL

  March 17, 2022, 3:48 PM – March 17, 2022, 4:00 PM

  Publication: --

  Presenters

  • Sumitabha Brahmachari

    • Rice University

  Authors

  • Sumitabha Brahmachari

    • Rice University

  • Tomer Markovich

    • Rice University

  • Frederick C MacKintosh

    • Rice University
    • Rice Univ

  • Jose N Onuchic

    • Rice University
    • Rice Univ

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• Phase separation and correlated motions in motorized genome

  ORAL

  March 17, 2022, 4:00 PM – March 17, 2022, 4:12 PM

  Presenters

  • Zhongling Jiang

    • Massachusetts Institute of Technology MI

  Authors

  • Zhongling Jiang

    • Massachusetts Institute of Technology MI

  • Bin Zhang

    • Massachusetts Institute of Technology MI
    • MIT

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• When motors collide: how transcription and loop-extruding cohesins organize chromatin

  ORAL

  March 17, 2022, 4:12 PM – March 17, 2022, 4:24 PM

  Presenters

  • Edward J Banigan

    • Massachusetts Institute of Technology
    • Massachusetts Institute of Technology MIT

  Authors

  • Edward J Banigan

    • Massachusetts Institute of Technology
    • Massachusetts Institute of Technology MIT

  • Wen Tang

    • Research Institute of Molecular Pathology, Vienna Biocenter

  • Aafke van den Berg

    • Massachusetts Institute of Technology

  • Roman Stocsits

    • Research Institute of Molecular Pathology, Vienna Biocenter

  • Gordana Wutz

    • Research Institute of Molecular Pathology, Vienna Biocenter

  • Hugo B Brandão

    • Massachusetts Institute of Technology
    • MIT

  • Georg Busslinger

    • Research Center for Molecular Medicine of the Austrian Academy of Sciences and the Medical University of Vienna

  • Jan-Michael Peters

    • Research Institute of Molecular Pathology, Vienna Biocenter

  • Leonid A Mirny

    • Massachusetts Institute of Technology MIT

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• Limited spreading enzyme stabilizes epigenetic memory

  ORAL

  March 17, 2022, 4:24 PM – March 17, 2022, 4:36 PM

  Presenters

  • Jeremy A Owen

    • Massachusetts Institute of Technology MIT

  Authors

  • Jeremy A Owen

    • Massachusetts Institute of Technology MIT

  • Dino Osmanovic

    • UCLA

  • Leonid A Mirny

    • Massachusetts Institute of Technology MIT

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• 4D Chromosome Organization: Combining Polymer Physics, Knot Theory and High Performance Computing

  ORAL

  March 17, 2022, 4:36 PM – March 17, 2022, 4:48 PM

  Publication: Four-dimensional chromosome reconstruction elucidates the spatiotemporal reorganization of the mammalian X chromosome
  A Lappala, CY Wang, A Kriz, H Michalk, K Tan, JT Lee, KY Sanbonmatsu,
  Proceedings of the National Academy of Sciences 118 (42)

  Presenters

  • Anna Lappala

    • Harvard University

  Authors

  • Anna Lappala

    • Harvard University

  • Jeannie T Lee

    • Harvard University

  • Kevin Tan

    • Harvard University

  • Karissa Sanbonmatsu

    • Los Alamos Natl Lab

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• Nucleosome-scale structure drives linker histone enrichment in heterochromatin in silico

  ORAL

  March 17, 2022, 4:48 PM – March 17, 2022, 5:00 PM

  Presenters

  • Aria E Coraor

    • University of Chicago

  Authors

  • Aria E Coraor

    • University of Chicago

  • Juan De Pablo

    • University of Chicago
    • Pritzker School of Molecular Engineering, University of Chicago

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• Differential regulation of alternative promoters emerges from unified kinetics of enhancer-promoter interaction

  ORAL

  March 17, 2022, 5:00 PM – March 17, 2022, 5:12 PM

  Publication: Jingyao Wang, Shihe Zhang, Hongfang Lu, Heng Xu, bioRxiv, 2021.06.03.446994v2.

  Presenters

  • Heng Xu

    • Shanghai Jiao Tong Univ

  Authors

  • Heng Xu

    • Shanghai Jiao Tong Univ

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• Mesoscale mixing of chromosomes

  ORAL

  March 17, 2022, 5:12 PM – March 17, 2022, 5:24 PM

  Presenters

  • Gaurav Bajpai

    • Weizmann Institute of Science

  Authors

  • Gaurav Bajpai

    • Weizmann Institute of Science

  • Samuel A Safran

    • Weizmann Institute of Science

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• Impact of cytosolic crowders on the morphology of bacterial chromosomes

  ORAL

  March 17, 2022, 5:24 PM – March 17, 2022, 5:36 PM

  Publication: Amit Kumar, Pinaki Swain, Bela M. Mulder, Debasish Chaudhuri. Impact of crowders on the morphology of bacterial chromosomes. Europhysics Letters, 2019; 128: 68003

  Presenters

  • Amit Kumar

    • Weizmann Institute of Science, Rehovot, Israel, 7610001
    • Weizmann Institute of Science

  Authors

  • Amit Kumar

    • Weizmann Institute of Science, Rehovot, Israel, 7610001
    • Weizmann Institute of Science

  • Pinaki Swain

    • McGill University, Montreal, Quebec H3A 0G4, Canada

  • Bela M Mulder

    • Institute AMOLF - Science Park 104, 1098XG Amsterdam, The Netherlands

  • Debasish Chaudhuri

    • Institute of Physics Bhubaneswar

  View abstract →