Biomolecular Phase Separation I - Interactions, Thermodynamics and Mechanics

FOCUS · S06 · ID: 46258






Presentations

  • ORAL · Invited

    Publication: 1. Zheng W*,Dignon GL*, Xu X, Regy RM, Best RB, Zheng W, Mittal J, "Molecular details of protein condensates probed by microsecond-long atomistic simulations",Journal of Physical Chemistry B,124, 11671-11679.
    2. Schuster BS*,Dignon GL*, Jahnke CN, Simpkins AG, Hammer DA, Good MC, Mittal J, "Identifying Sequence Perturbations to an Intrinsically Disordered Protein that Determine its Phase Separation Behavior",Proceedings of the National Academy of Sciences,117, 11421-11431.
    3. Zheng W, Dignon GL, Brown M, Kim YC, Mittal J, "Hydropathy patterning complements charge patterning to describe conformational preferences of disordered proteins",Journal of Physical Chemistry Letters,11, 3408-415.
    4. Dignon GL*, Zheng W*, Kim YC, Mittal J, "Temperature controlled liquid-liquid phase separation of disordered proteins",ACS Central Science,5, 821-830.
    5. Dignon GL*, Zheng W*, Best RB, Kim YC, Mittal J, "Relation between single-molecule properties and phase behavior of intrinsically disordered proteins",Proceedings of theNational Academy of Sciences,115, 9929-9934.
    6. Dignon GL*, Zheng W*, Kim YC, Best RB, Mittal J, "Sequence determinants of protein phase behavior from a coarse-grained model",PLOS Computational Biology,14,e1005941.

    Presenters

    • Gregory Dignon

      • Stony Brook University (SUNY)

    Authors

    • Gregory Dignon

      • Stony Brook University (SUNY)

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  • ORAL

    Publication: Ushnish Rana, Clifford P. Brangwynne, and Athanassios Z. Panagiotopoulos , "Phase separation vs aggregation behavior for model disordered proteins", J. Chem. Phys. 155, 125101 (2021) https://doi.org/10.1063/5.0060046

    Presenters

    • Ushnish Rana

      • Princeton University

    Authors

    • Ushnish Rana

      • Princeton University
    • Cliff Brangwynne

      • Princeton University
    • Athanassios Panagiotopoulos

      • Princeton University

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  • ORAL

    Presenters

    • Andrej Kosmrlj

      • Princeton University
      • Princeton

    Authors

    • Josep Bataller i Umbert

      • Polytechnic University of Catalonia
    • Mikko Haataja

      • Princeton University
    • Sheng Mao

      • Peking University
    • Andrej Kosmrlj

      • Princeton University
      • Princeton

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  • ORAL

    Publication: On the interplay between phase separation and aggregation [in prep.]

    Presenters

    • Giacomo Bartolucci

      • Max Planck Institute for the Physics of Complex Systems

    Authors

    • Giacomo Bartolucci

      • Max Planck Institute for the Physics of Complex Systems
    • Thomas C Michaels

      • Harvard University
    • Christoph A Weber

      • University of Augsburg, Institute of Physics
      • Institute of Physics, University of Augsburg
      • Institute of Physics University of Augsburg

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  • ORAL

    Publication: - Joseph, Reinhardt et al., Physics driven coarse-grained model for biomolecular phase separation with near-quantitative accuracy, Nat.Comput. Sci., 2021 (in press).
    - Lichtinger et al, Targeted modulation of protein liquid–liquid phase separation by evolution of amino-acid sequence, Plos Comp Biol, 2021

    Presenters

    • Maria J Maristany

      • Univ of Cambridge

    Authors

    • Maria J Maristany

      • Univ of Cambridge
    • Jerelle A Joseph

      • University of Cambridge
    • Rosana Collepardo-Guevara

      • University of Cambridge
    • Aleks Reinhardt

      • University of Cambridge

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