Morphogenesis II

ORAL · K05 · ID: 46394

Presentations

  • ORAL

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    Publication: Global constraints within the developmental program of the Drosophila wing by Vasyl Alba, James E Carthew, Richard W Carthew, Madhav Mani
    eLife 2021;10:e66750 DOI: 10.7554/eLife.66750

    Presenters

    • Vasyl Alba

      • Northwestern University

    Authors

    • Vasyl Alba

      • Northwestern University

    • James E Carthew

      • University of Pennsylvania

    • Richard Carthew

      • Northwestern University

    • Madhav Mani

      • Northwestern University

    View abstract →

  • ORAL

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    Publication: Submitted manuscript: Hannah J. Gustafson, Nikolas Claussen, Stefano De Renzis and Sebastian J. Streichan - "Patterned mechanical feedback establishes a global myosin gradient"

    Presenters

    • Nikolas H Claussen

      • University of California, Santa Barbara

    Authors

    • Nikolas H Claussen

      • University of California, Santa Barbara

    • Matthew F Lefebvre

      • University of California, Santa Barbara

    • Hannah J Gustavson

      • University of California, Santa Barbara

    • Noah P Mitchell

      • University of California, Santa Barbara

    • Stefano De Renzis

      • EMBL Heidelberg

    • Boris I Shraiman

      • University of California, Santa Barbara

    • Sebastian J Streichan

      • University of California, Santa Barbara
      • University of California, Santa barbara

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  • ORAL

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    Publication: https://doi.org/10.1016/j.cdev.2021.203721

    Presenters

    • Gonca Erdemci-Tandogan

      • University of Toronto, Institute of Biomedical Engineering

    Authors

    • Gonca Erdemci-Tandogan

      • University of Toronto, Institute of Biomedical Engineering

    • Jessica C Yu

      • University of Toronto, Institute of Biomedical Engineering

    • Negar Balaghi

      • University of Toronto, Institute of Biomedical Engineering

    • Veronica Castle

      • University of Toronto, Institute of Biomedical Engineering

    • Rodrigo Fernandez-Gonzalez

      • University of Toronto, Institute of Biomedical Engineering

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  • ORAL

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    Presenters

    • Behzad Golshaei

      • Department of Biomedical Engineering, Duke University
      • Duke University

    Authors

    • Behzad Golshaei

      • Department of Biomedical Engineering, Duke University
      • Duke University

    • Chonglin Guan

      • Physics department, Duke University
      • Duke University

    • An T Pham

      • an.t.pham@duke.edu

    • Janice M Crawford

      • Department of Biology, Duke University

    • Daniel P Kiehart

      • Department of Biology, Duke University

    • Christoph F Schmidt

      • Department of Biomedical Engineering, Duke University; Department of Physics, Duke University; Department of Biology, Duke University
      • Duke University
      • Department of Physics and Soft Matter Center, Duke University, Durham, NC 27708, USA

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  • ORAL

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    Presenters

    • Noah P Mitchell

      • University of California, Santa Barbara

    Authors

    • Noah P Mitchell

      • University of California, Santa Barbara

    • Dillon J Cislo

      • University of California, Santa Barbara

    • Suraj Shankar

      • Harvard University

    • Yuzheng Lin

      • University of California, Santa Barbara

    • Boris I Shraiman

      • University of California, Santa Barbara

    • Sebastian J Streichan

      • University of California, Santa Barbara
      • University of California, Santa barbara

    View abstract →

  • ORAL

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    Publication: Lumenization an epithelium is an essential and ubiquitous step across the morphogenic processes needed to produce hollow structures such as alveoli, kidney ducts, and the gut. Once a lumen is established, it undergoes cycles of swelling and relaxation that precede multiple critical developmental events such as branching. Here, we show that electrical cues can drive the swelling of homotypic epithelial cysts and intestinal organoids. This behavior appears to be driven by electrical modulation of key ion channels responsible for chloride ion transport such as CFTR, which we demonstrate through the use of targeted ion channel inhibitors. Interestingly, the level of swelling varies directly with the strength of the electric field, allowing us to program both the rate of growth and the overall size of a spherical cyst or organoid. The rate of swelling is too rapid to implicate cell proliferation, so we hypothesize hyperelastic deformation of the epithelium. To investigate this, we modify a simple energy-minimization model to consider the effect of stimulation on osmotic pressure, hydrostatic pressure, and ion-mediated pumping to predict accelerated cyst swelling.

    Presenters

    • Isaac B Breinyn

      • Princeton University

    Authors

    • Isaac B Breinyn

      • Princeton University

    • Gawoon Shim

      • Princeton University

    • Daniel J Cohen

      • Princeton University

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  • ORAL

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    Presenters

    • Hungtang Ko

      • Georgia Institute of Technology

    Authors

    • Hungtang Ko

      • Georgia Institute of Technology

    • Keyana Komilian

      • Georgia Institute of Technology

    • Leo Hollingworth

      • Georgia Institute of Technology

    • Elliot P Willner

      • Georgia Institute of Technology

    • David L Hu

      • Georgia Institute of Technology

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  • ORAL

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    Presenters

    • Jonathan Colen

      • University of Chicago

    Authors

    • Jonathan Colen

      • University of Chicago

    • Noah P Mitchell

      • University of California, Santa Barbara

    • Nikolas H Claussen

      • University of California, Santa Barbara

    • Marion Raich

      • TU Munich

    • Sebastian J Streichan

      • University of California, Santa Barbara
      • University of California, Santa barbara

    • Vincenzo Vitelli

      • University of Chicago

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  • ORAL

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    Presenters

    • Marianne Bauer

      • Princeton University

    Authors

    • Marianne Bauer

      • Princeton University

    • Mariela D Petkova

      • Harvard University

    • Thomas Gregor

      • Princeton University
      • Department of Physics Princeton University
      • Princeton University, Princeton, NJ, USA and Institut Pasteur, Paris, France

    • Eric F Wieschaus

      • Department of Molecular Biology Princeton University
      • Princeton University

    • William S Bialek

      • Princeton University

    View abstract →

  • ORAL

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    Presenters

    • Abhijeet Krishna

      • Max Planck Institute of Molecular Cell Biology and Genetics

    Authors

    • Abhijeet Krishna

      • Max Planck Institute of Molecular Cell Biology and Genetics

    • Jana Fuhrmann

      • Max Planck Institute of Molecular Cell Biology and Genetics

    • Charlie Duclut

      • Max Planck Institute for the Physics of Complex Systems, Dresden, Germany
      • Max Planck Institute of Physics of Complex Systems
      • Max Planck Institute for the Physics of Complex Systems

    • Frank Jülicher

      • Max Planck Institut for the Physics of Complex Systems, Dresden
      • Max Planck Institute for the Physics of Complex Systems
      • Max Planck Institute of Physics of Complex Systems

    • Natalie Dye

      • Physics of Life, TU Dresden

    • Carl D Modes

      • Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany
      • Max Planck Institute of Molecular Cell Biology and Genetics
      • MPI-CBG, MPI-PKS, CSBD
      • Max Planck Institut for Molecular Cell Biology and Genetics (MPI-CBG), 01307 Dresden, Germany.
      • Max Planck Institute for Molecular Cell Biology and Genetics

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  • ORAL

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    Publication: KS Iyer, C Prabhakara, S Mayor, M Rao. Cellular Compartmentalisation and Receptor Promiscuity as a strategy for accuracy and robustness in Positional Inference during Morphogenesis (in preparation)

    Presenters

    • Krishnan S Iyer

      • Tata Institute of Fundamental Research (
      • Simons Center for the Study of Living Machines, National Center for Biological Sciences - TIFR

    Authors

    • Krishnan S Iyer

      • Tata Institute of Fundamental Research (
      • Simons Center for the Study of Living Machines, National Center for Biological Sciences - TIFR

    • Chaitra Prabhakara

      • National Center for Biological Sciences - TIFR

    • Madan Rao

      • Simons Centre for the Study of Living Machines, National Centre for Biological Sciences (TIFR), Bangalore 560065, India
      • National Center For Biological Sciences, Bengaluru
      • Simons Center for the Study of Living Machines, National Center for Biological Sciences - TIFR

    • Satyajit Mayor

      • National Center for Biological Sciences - TIFR

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  • ORAL

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    Presenters

    • Luyi Qiu

      • Harvard University

    Authors

    • Luyi Qiu

      • Harvard University

    • Cesar L Pastrana

      • Technical University of Munich

    • Ulrich Gerland

      • Technical University of Munich

    • Shahaf Armon

      • Weizmann Institute of Science

    • Ariel Amir

      • Harvard University

    View abstract →