Emergent Biomolecular Assembly

Presentations

• Quinary structure modulates protein sequence stability in vivo

  ORAL · Invited

  March 14, 2022, 11:30 AM – March 14, 2022, 12:06 PM

  Publication: Sternke, M., Barrick, D., Gruebele, M.*, Davis, C.M.* "Quinary structure modulates protein sequence stability in vivo," in preparation.

  Presenters

  • Caitlin Davis

    • Yale

  Authors

  • Caitlin Davis

    • Yale

  • Martin Gruebele

    • University of Illinois at Urbana-Champaign

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• Optimizing kinetics of hetero-subunit assembly using differentiable models

  ORAL

  March 14, 2022, 12:06 PM – March 14, 2022, 12:18 PM

  Presenters

  • Adip Jhaveri

    • Johns Hopkins University

  Authors

  • Adip Jhaveri

    • Johns Hopkins University

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• Nature of size fluctuations in filamentous cytoskeletal structures

  ORAL

  March 14, 2022, 12:18 PM – March 14, 2022, 12:30 PM

  Presenters

  • Aldric Rosario

    • Brandeis University

  Authors

  • Aldric Rosario

    • Brandeis University

  • Shane G McInally

    • Brandeis University

  • Bruce L Goode

    • Brandeis University

  • Jane Kondev

    • Brandeis University
    • Brandeis Univ

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• Predicting Timescales of DNA Mediated Protein Assembly

  ORAL

  March 14, 2022, 12:30 PM – March 14, 2022, 12:42 PM

  Presenters

  • Mankun Sang

    • Johns Hopkins University

  Authors

  • Mankun Sang

    • Johns Hopkins University

  • Margaret E Johnson

    • Johns Hopkins University

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• Active nuclear transport in living cells: dynamics and steady-state profiles of cargo concentrations

  ORAL

  March 14, 2022, 12:42 PM – March 14, 2022, 12:54 PM

  Presenters

  • Alex S Rautu

    • Simons Foundation

  Authors

  • Alex S Rautu

    • Simons Foundation

  • Michael J Shelley

    • Courant Inst. (NYU), Flatiron Inst. (SF)
    • Flatiron Institute and New York University
    • Flatiron Institute and Courant Institute, New York University
    • Flatiron Institute

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• Acentrosomal spindles assemble from branching nucleation near chromosomes

  ORAL

  March 14, 2022, 12:54 PM – March 14, 2022, 1:06 PM

  Presenters

  • Bernardo Gouveia

    • Princeton University

  Authors

  • Bernardo Gouveia

    • Princeton University

  • Sagar U Setru

    • Princeton University

  • Joshua W Shaevitz

    • Princeton University

  • Howard A Stone

    • Princeton
    • Princeton University

  • Sabine Petry

    • Princeton University

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• The roles of stoichiometric crowding and protein-protein interactions in accelerating translation elongation rates in E. coli

  ORAL

  March 14, 2022, 1:06 PM – March 14, 2022, 1:18 PM

  Presenters

  • Jennifer L Hofmann

    • Stanford University

  Authors

  • Jennifer L Hofmann

    • Stanford University

  • Roseanna N Zia

    • Stanford Univ
    • Stanford University

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• LIM domain proteins localize to strained actin, focal adhesions and adherens junctions in a tension-dependent manner

  ORAL

  March 14, 2022, 1:18 PM – March 14, 2022, 1:30 PM

  Publication: Part of this work is published:
  Winkelman, J. D., Anderson, C. A., Suarez, C., Kovar, D. R., & Gardel, M. L. (2020). Evolutionarily diverse LIM domain-containing proteins bind stressed actin filaments through a conserved mechanism. Proceedings of the National Academy of Sciences, 117(41), 25532-25542.

  Presenters

  • Shailaja Seetharaman

    • University of Chicago

  Authors

  • Shailaja Seetharaman

    • University of Chicago

  • Jonathan Winkelman

    • University of Chicago

  • Yvonne Beckham

    • University of Chicago

  • Margaret Gardel

    • University of Chicago

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• Measuring Weak Protein-Protein Interactions Using a Mechanically Transduced Immunosorbent Assay

  ORAL

  March 14, 2022, 1:30 PM – March 14, 2022, 1:42 PM

  Publication: https://elifesciences.org/articles/67525#metrics

  Presenters

  • Joshua P Steimel

    • University of the Pacific

  Authors

  • Joshua P Steimel

    • University of the Pacific

  • Christopher J Petell

    • UNC

  • Joe Harrison

    • UOP

  • Brian Strahl

    • UNC

  • Michael Pappas

    • UOP

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• Evolutionary advantage of a dissociative search mechanism in DNA mismatch repair

  ORAL

  March 14, 2022, 1:42 PM – March 14, 2022, 1:54 PM

  Publication: Crocker, K., London, J., Medina, A., Fishel, R., & Bundschuh, R. (2021). Evolutionary advantage of a dissociative search mechanism in DNA mismatch repair. Physical Review E, 103(5), 052404.

  Presenters

  • Kyle Crocker

    • University of Chicago

  Authors

  • Kyle Crocker

    • University of Chicago

  • James London

    • Ohio State University

  • Andres A Medina

    • Ohio State Univ - Columbus

  • Richard Fishel

    • Ohio State University

  • Ralf Bundschuh

    • Ohio State University
    • Ohio State Univ - Columbus

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• Steps of actin filament branch formation by Arp2/3 complex investigated with coarse-grained molecular dynamics

  ORAL

  March 14, 2022, 1:54 PM – March 14, 2022, 2:06 PM

  Presenters

  • Shuting Zhang

    • Lehigh Univ
    • Lehigh University

  Authors

  • Dimitrios Vavylonis

    • Lehigh University

  • Shuting Zhang

    • Lehigh Univ
    • Lehigh University

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• Overlooked transcription factor crosslinking and steric forces can coordinate chromatin and TAD organization

  ORAL

  March 14, 2022, 2:06 PM – March 14, 2022, 2:18 PM

  Publication: Yan, W., Ansari, S., Lamson, A., Glaser, M. A., Betterton, M., & Shelley, M. J. (2021). aLENS: towards the cellular-scale simulation of motor-driven cytoskeletal assemblies. arXiv preprint arXiv:2109.08206.

  Presenters

  • Adam R Lamson

    • Simons Foundation

  Authors

  • Adam R Lamson

    • Simons Foundation

  • Wen Yan

    • Flatiron Institute

  • Alex S Rautu

    • Simons Foundation

  • Michael J Shelley

    • Courant Inst. (NYU), Flatiron Inst. (SF)
    • Flatiron Institute and New York University
    • Flatiron Institute and Courant Institute, New York University
    • Flatiron Institute

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• Understanding the Unfolding Mechanisms of ??D Crystallin using Molecular Dynamics Simulations

  ORAL

  March 14, 2022, 2:18 PM – March 14, 2022, 2:30 PM

  Presenters

  • DEEPSHIKHA GHOSH

    • IIT Gandhinagar

  Authors

  • DEEPSHIKHA GHOSH

    • IIT Gandhinagar

  • Kandarp Sojitra

    • Texas A&M University, USA

  • Manish Agarwal

    • Indian Institute of Technology Delhi
    • IIT Delhi

  • Mithun Radhakrishna

    • Assistant Professor
    • Indian Institute of technology Gandhinagar
    • IIT Gandhinagar

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