Phase sensitive X-ray imaging experiments with structured illumination and polycapillary optics for clinical application

ORAL

Abstract

X -ray phase images of soft tissue provide higher image contrast than conventional images because the difference in phase imparted to X-rays by similar soft tissues is large compared to the difference in attenuation. However, phase imaging has found limited clinical use due to requirements on x-ray coherence that may not be easily translated to clinical practice or the need for precision gratings with limited field of view. Instead, we will discuss experiments to achieve practicable phase imaging that employ a conventional source to create structured illumination with a simple wire mesh. Polycapillary optics are employed to enhance coherence. A deconvolution method minimizes the effect of spurious gradients due to the finite source size and camera resolution. We will present results from a reconstruction method that produces scatter free absorption, phase and scatter amplitude images simultaneously.

*This work was supported in part by the New York State Department of Health (DOH01-C33920GG-3450000).

Presenters

  • Uttam Pyakurel

    • University at Albany

Authors

  • Uttam Pyakurel

    • University at Albany
  • Weiyuan Sun

    • University at Albany
  • Pikting Cheung

    • University at Albany
  • Xiaoyun Zhang

    • Nuclear Science and Technology, Beijing Normal University
  • Carolyn MacDonald

    • University at Albany
  • Jonathan C Petruccelli

    • University at Albany