Immune Sensing and Response I

Presentations

• To die or not to die: Cell decision-making in the face of viral threat

  Invited

  March 17, 2021, 8:00 AM – March 17, 2021, 8:36 AM

  Presenters

  • Jennifer Oyler-Yaniv

    • Systems Biology, Harvard Medical School

  Authors

  • Jennifer Oyler-Yaniv

    • Systems Biology, Harvard Medical School

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• A data-driven model for somatic hypermutation of B-cell

  ORAL

  March 17, 2021, 8:36 AM – March 17, 2021, 8:48 AM

  Presenters

  • Natanael Spisak

    • CNRS

  Authors

  • Natanael Spisak

    • CNRS

  • Aleksandra Walczak

    • Laboratoire de physique de l’Ecole normale superieure, CNRS
    • CNRS
    • Ecole Normale Superieure
    • Département de Physique, École Normale Supérieure
    • Dept of Physics, École Normale Supérieure

  • Thierry Mora

    • CNRS
    • Ecole Normale Superieure

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• Statistical analysis of sharing in antibody repertoires

  ORAL

  March 17, 2021, 8:48 AM – March 17, 2021, 9:00 AM

  Presenters

  • Maria Ruiz Ortega

    • Département de Physique, École Normale Supérieure

  Authors

  • Maria Ruiz Ortega

    • Département de Physique, École Normale Supérieure

  • Thierry Mora

    • Ecole Normale Superieure
    • Département de Physique, École Normale Supérieure

  • Aleksandra Walczak

    • Laboratoire de physique de l’Ecole normale superieure, CNRS
    • CNRS
    • Ecole Normale Superieure
    • Département de Physique, École Normale Supérieure
    • Dept of Physics, École Normale Supérieure

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• How the T cell signaling network processes information to discriminate between self and agonist ligands.

  ORAL

  March 17, 2021, 9:00 AM – March 17, 2021, 9:12 AM

  Presenters

  • Raman Ganti

    • Massachusetts Institute of Technology MIT

  Authors

  • Raman Ganti

    • Massachusetts Institute of Technology MIT

  • Wan-Lin Lo

    • Division of Rheumatology, University of California, San Francisco

  • Darren B. McAffee

    • Department of Chemistry, University of California, Berkeley

  • Jay T. Groves

    • Department of Chemistry, University of California, Berkeley

  • Arthur Weiss

    • Division of Rheumatology, University of California, San Francisco

  • Arup K Chakraborty

    • Massachusetts Institute of Technology MIT
    • MIT

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• Statistics of large scale insertions in B-cell receptors

  ORAL

  March 17, 2021, 9:12 AM – March 17, 2021, 9:24 AM

  Presenters

  • Cosimo Lupo

    • CNRS

  Authors

  • Cosimo Lupo

    • CNRS

  • Thierry Mora

    • Laboratoire de physique de l’Ecole normale superieure, CNRS
    • CNRS

  • Aleksandra Walczak

    • Laboratoire de physique de l’Ecole normale superieure, CNRS
    • CNRS
    • Ecole Normale Superieure
    • Département de Physique, École Normale Supérieure
    • Dept of Physics, École Normale Supérieure

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• Modularity optimizes target recognition in the CRISPR-Cas immune system

  ORAL

  March 17, 2021, 9:24 AM – March 17, 2021, 9:36 AM

  Presenters

  • Melia Bonomo

    • Rice University

  Authors

  • Melia Bonomo

    • Rice University

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• A scaling law in CRISPR repertoire sizes arises from the avoidance of autoimmunity

  ORAL

  March 17, 2021, 9:36 AM – March 17, 2021, 9:48 AM

  Presenters

  • Andreas Mayer

    • Princeton University

  Authors

  • Hanrong Chen

    • University of Pennsylvania

  • Andreas Mayer

    • Princeton University

  • Vijay Balasubramanian

    • University of Pennsylvania
    • Physics Department, University of Pennsylvenia

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• Stochasticity influences the efficacy of simulated bacteriotherapies

  ORAL

  March 17, 2021, 9:48 AM – March 17, 2021, 10:00 AM

  Presenters

  • Eric Jones

    • Physics, Simon Fraser University

  Authors

  • Eric Jones

    • Physics, Simon Fraser University

  • David Sivak

    • Simon Fraser Univ
    • Physics, Simon Fraser Univ
    • Physics, Simon Fraser University

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• Inferring T-cells repertoire dynamics for healthy individuals.

  ORAL

  March 17, 2021, 10:00 AM – March 17, 2021, 10:12 AM

  Presenters

  • Meriem Bensouda Koraichi

    • Ecole Normale Superieure

  Authors

  • Meriem Bensouda Koraichi

    • Ecole Normale Superieure

  • Thomas Dupic

    • Harvard University

  • Thierry Mora

    • CNRS
    • Ecole Normale Superieure

  • Aleksandra Walczak

    • Laboratoire de physique de l’Ecole normale superieure, CNRS
    • CNRS
    • Ecole Normale Superieure
    • Département de Physique, École Normale Supérieure
    • Dept of Physics, École Normale Supérieure

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• Learning and memory in molecular recognition: from olfactory to immune system

  ORAL

  March 17, 2021, 10:12 AM – March 17, 2021, 10:24 AM

  Presenters

  • Oskar Schnaack

    • Max Planck Institute for Dynamics and Self-Organization

  Authors

  • Oskar Schnaack

    • Max Planck Institute for Dynamics and Self-Organization

  • Luca Peliti

    • Santa Marinella Research Institute

  • Armita Nourmohammad

    • Max Planck Institute for Dynamics and Self-Organization
    • Physics Department, University of Washington
    • University of Washington

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• Deep generative selection models of T and B cell receptor repertoires with soNNia

  ORAL

  March 17, 2021, 10:24 AM – March 17, 2021, 10:36 AM

  Presenters

  • Giulio Isacchini

    • CNRS

  Authors

  • Giulio Isacchini

    • CNRS

  • Thierry Mora

    • CNRS
    • Ecole Normale Superieure

  • Aleksandra Walczak

    • Laboratoire de physique de l’Ecole normale superieure, CNRS
    • CNRS
    • Ecole Normale Superieure
    • Département de Physique, École Normale Supérieure
    • Dept of Physics, École Normale Supérieure

  • Armita Nourmohammad

    • Physics, University of Washington

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