Game Theory Cancer Models of Cancer Cell-Stromal Cell Dynamics using Interacting Particle Systems

ORAL

Abstract

We describe an evolutionary game theory model that has been used to predict the population dynamics of interacting cancer and stromal cells. We first consider the mean field case assuming homogeneous and non-discrete populations. Interacting Particle Systems (IPS) are then presented as a discrete and spatial alternative to the mean field approach. Finally, we discuss cases where IPS gives results different from the mean field approach.

*This work was supported by NSF PHY-1659940.

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Presenters

  • Yusha Y Sun

    • Medical School, University of Pennsylvania

Authors

  • Yusha Y Sun

    • Medical School, University of Pennsylvania

  • Yinan Zheng

    • Princeton University

  • Gonzalo Torga

    • UCL Cancer Institute, University College London

  • Kenneth J. Pienta

    • Urology, Johns Hopkins Medical Institute

  • Robert Austin

    • Princeton University