Macromolecular Phase Separation I

Presentations

• Decoding the physical principles of biomolecular phase separation

  Invited

  March 15, 2021, 8:00 AM – March 15, 2021, 8:36 AM

  Presenters

  • Yaojun Zhang

    • Princeton University

  Authors

  • Yaojun Zhang

    • Princeton University

  • Bin Xu

    • Princeton University

  • Benjamin Weiner

    • Princeton University

  • Yigal Meir

    • Ben Gurion University of the Negev
    • Department of Physics, Ben-Gurion University of the Negev
    • Ben-Gurion University

  • Ned S Wingreen

    • Princeton University

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• Reentrant transitions in protein phase-separation: segregation vs. association

  ORAL

  March 15, 2021, 8:36 AM – March 15, 2021, 8:48 AM

  Presenters

  • Dan Deviri

    • Weizmann Institute of Science

  Authors

  • Dan Deviri

    • Weizmann Institute of Science

  • Samuel Safran

    • Weizmann Institute of Science
    • Chemical and Biological Physics, Weizmann Institute of Science

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• Fusion of Biomolecular Condensates

  ORAL

  March 15, 2021, 8:48 AM – March 15, 2021, 9:00 AM

  Presenters

  • Mahdiye Ijavi

    • ETH Zurich

  Authors

  • Mahdiye Ijavi

    • ETH Zurich

  • Flurin Sturzenegger

    • University of Zurich

  • Benjamin Schuler

    • University of Zurich

  • Eric R Dufresne

    • ETH Zurich
    • Material Sciences, ETH Zürich

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• Novel “dark state” phosphate cluster formation in aqueous solution

  ORAL

  March 15, 2021, 9:00 AM – March 15, 2021, 9:12 AM

  Presenters

  • Joshua Straub

    • University of California, Santa Barbara

  Authors

  • Joshua Straub

    • University of California, Santa Barbara

  • Mesopotamia Nowotarski

    • University of California, Santa Barbara

  • Jiaqi Lu

    • New York University

  • Matthew Helgeson

    • Chemical Engineering, University of California, Santa Barbara
    • University of California, Santa Barbara
    • University of California Santa Barbara
    • University of Califronia Santa Barbara

  • Alexej Jerschow

    • New York University

  • Songi Han

    • University of California, Santa Barbara

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• Non-equilibrium regulation and organization of transcriptional condensates by RNA synthesis

  ORAL

  March 15, 2021, 9:12 AM – March 15, 2021, 9:24 AM

  Presenters

  • Krishna Shrinivas

    • Harvard University

  Authors

  • Krishna Shrinivas

    • Harvard University

  • Jonathan Henninger

    • Whitehead Institute for Biomedical Research

  • Ozgur Oksuz

    • Whitehead Institute for Biomedical Research

  • Halima Schede

    • MIT

  • Phillip Sharp

    • MIT

  • Richard Young

    • Whitehead Institute for Biomedical Research

  • Arup K Chakraborty

    • Massachusetts Institute of Technology MIT
    • MIT

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• Quantitative Theory for the Diffusive Exchange Dynamics of Liquid Condensates

  ORAL

  March 15, 2021, 9:24 AM – March 15, 2021, 9:36 AM

  Presenters

  • Lars Hubatsch

    • Max Planck Institute for the Physics of Complex Systems

  Authors

  • Lars Hubatsch

    • Max Planck Institute for the Physics of Complex Systems

  • Louise Jawerth

    • Physics, Leiden University
    • Max Planck Institute for the Physics of Complex Systems; Max Planck Institute of Molecular Cell Biology and Genetics
    • Max Planck Institute for the Physics of Complex Systems

  • Celina Love

    • Max Planck Institute for Cell Biology and Genetics

  • Jonathan Bauermann

    • Max Planck Institute for the Physics of Complex Systems

  • TY Dora Tang

    • Max Planck Institute for Cell Biology and Genetics

  • Stefano Bo

    • Max Planck Institute for the Physics of Complex Systems

  • Anthony A Hyman

    • Max Planck Institute for Cell Biology and Genetics
    • Max Planck Institute for Molecular Cell Biology and Genetics; Physics of Life, TU-Dresden
    • Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

  • Christoph Weber

    • Max Planck Institute for the Physics of Complex Systems
    • Max Planck Institute for Physics of Complex Systems

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• Surface condensation of a pioneer transcription factor on DNA

  ORAL

  March 15, 2021, 9:36 AM – March 15, 2021, 9:48 AM

  Presenters

  • Jose Morin

    • Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

  Authors

  • Jose Morin

    • Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

  • Sina Wittmann

    • Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

  • Sandeep Choubey

    • Max Planck Institute for the Physics of Complex Systems

  • Adam Klosin

    • Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

  • Stefan Golfier

    • Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

  • Anthony A Hyman

    • Max Planck Institute for Cell Biology and Genetics
    • Max Planck Institute for Molecular Cell Biology and Genetics; Physics of Life, TU-Dresden
    • Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

  • Frank Julicher

    • Max Planck Institute for Physics of Complex Systems
    • Max Planck Institute for the Physics of Complex Systems
    • Max Planck Institute for Physics of Complex Systems, Noethnitzer Strasse 38, 01187 Dresden, Germany
    • MPI PKS, Dresden

  • Stephan Grill

    • Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

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• Quantitative phase microscopy enables precise and efficient determination of biomolecular condensate composition

  ORAL

  March 15, 2021, 9:48 AM – March 15, 2021, 10:00 AM

  Presenters

  • Patrick M. McCall

    • Max Planck Institute of Molecular Cell Biology and Genetics; Max Planck Institute for the Physics of Complex Systems; Center for Systems Biology Dresden

  Authors

  • Patrick M. McCall

    • Max Planck Institute of Molecular Cell Biology and Genetics; Max Planck Institute for the Physics of Complex Systems; Center for Systems Biology Dresden

  • Kyoohyun Kim

    • Max Planck Institute for the Science of Light; BIOTEC, TU-Dresden

  • Anatol W. Fritsch

    • Max Planck Institute for Cell Biology and Genetics
    • Max Planck Institute of Molecular Cell Biology and Genetics

  • Juan M. Iglesias-Artola

    • Max Planck Institute of Molecular Cell Biology and Genetics

  • Louise Jawerth

    • Physics, Leiden University
    • Max Planck Institute for the Physics of Complex Systems; Max Planck Institute of Molecular Cell Biology and Genetics
    • Max Planck Institute for the Physics of Complex Systems

  • Jie Wang

    • Max Planck Institute of Molecular Cell Biology and Genetics

  • Martine Ruer

    • Max Planck Institute of Molecular Cell Biology and Genetics

  • Andrey Poznyakovskiy

    • Max Planck Institute of Molecular Cell Biology and Genetics

  • Jan Peychl

    • Max Planck Institute of Molecular Cell Biology and Genetics

  • Jochen Guck

    • Max Planck Institute for the Science of Light; BIOTEC, TU-Dresden; Physics of Life, TU-Dresden

  • Simon Alberti

    • BIOTEC, TU-Dresden; Physics of Life, TU-Dresden

  • Anthony A Hyman

    • Max Planck Institute for Cell Biology and Genetics
    • Max Planck Institute for Molecular Cell Biology and Genetics; Physics of Life, TU-Dresden
    • Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

  • Jan Brugués

    • Max Planck Institute of Molecular Cell Biology and Genetics; Max Planck Institute for the Physics of Complex Systems; Center for Systems Biology Dresden; Physics of Life, TU-

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• Elastically limited liquid-liquid phase separation

  ORAL

  March 15, 2021, 10:00 AM – March 15, 2021, 10:12 AM

  Presenters

  • Pierre Ronceray

    • Princeton University
    • Princeton
    • Center for the Physics of Biological Function, Princeton University

  Authors

  • Pierre Ronceray

    • Princeton University
    • Princeton
    • Center for the Physics of Biological Function, Princeton University

  • Sheng Mao

    • Peking University

  • Andrej Kosmrlj

    • Princeton University

  • Mikko Haataja

    • Princeton University

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• Phase separation controlled by molecular transitions

  ORAL

  March 15, 2021, 10:12 AM – March 15, 2021, 10:24 AM

  Presenters

  • Giacomo Bartolucci

    • Max Planck Institute for Physics of Complex Systems
    • Max Planck Institute for the Physics of Complex Systems

  Authors

  • Giacomo Bartolucci

    • Max Planck Institute for Physics of Complex Systems
    • Max Planck Institute for the Physics of Complex Systems

  • Omar Adame-Arana

    • Weizmann Institute of Science
    • Max Planck Institute for Cell Biology and Genetics

  • Xueping Zhao

    • Max Planck Institute for Physics of Complex Systems
    • Max Planck Institute for the Physics of Complex Systems

  • Christoph Weber

    • Max Planck Institute for the Physics of Complex Systems
    • Max Planck Institute for Physics of Complex Systems

  View abstract →

• Liquid condensates increase potency of amyloid fibril inhibitors

  ORAL

  March 15, 2021, 10:24 AM – March 15, 2021, 10:36 AM

  Presenters

  • Thomas Michaels

    • School of Engineering and Applied Sciences, Harvard University
    • Applied Mathematics Department, Harvard University
    • Harvard University

  Authors

  • Thomas Michaels

    • School of Engineering and Applied Sciences, Harvard University
    • Applied Mathematics Department, Harvard University
    • Harvard University

  • Lakshminarayanan Mahadevan

    • Harvard University

  • Christoph Weber

    • Max Planck Institute for the Physics of Complex Systems
    • Max Planck Institute for Physics of Complex Systems

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• Characterization of the functional relevance of intranuclear transcription factor aggregates in living fly embryos

  ORAL

  March 15, 2021, 10:36 AM – March 15, 2021, 10:48 AM

  Presenters

  • Rahul Munshi

    • Princeton University

  Authors

  • Rahul Munshi

    • Princeton University

  • Michal Levo

    • Princeton University

  • Eric F. Wieschaus

    • Princeton University

  • Thomas Gregor

    • Princeton University
    • Physics, Genomics, and Stem Cell Biology, Princeton University and Institut Pasteur
    • Joseph Henry Laboratories of Physics and Lewis-Sigler Institute for Integrative Genomics, Princeton University

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• Phase-separated compartments as biochemical reactors

  ORAL

  March 15, 2021, 10:48 AM – March 15, 2021, 11:00 AM

  Presenters

  • Sudarshana Laha

    • Max Planck Institute for Physics of Complex Systems

  Authors

  • Sudarshana Laha

    • Max Planck Institute for Physics of Complex Systems

  • Thomas Michaels

    • School of Engineering and Applied Sciences, Harvard University
    • Applied Mathematics Department, Harvard University
    • Harvard University

  • Christoph Weber

    • Max Planck Institute for the Physics of Complex Systems
    • Max Planck Institute for Physics of Complex Systems

  View abstract →