Bio-Sensors Based on Organic Electrochemical Transistors

Organic Electrochemical Transistors (OECTs) are capable of sensing a wide variety of biomolecules such as Glutamate, Acetylcholine [1], Lactic acids [2], or Glucose [3]. However, despite this success, the precise sensing mechanisms is still under discussion. This lack of understanding precludes a targeted design of OECT applications and currently limits the sensitivity of these devices. Here, we study the working mechanism of OECT based neurotransmitter (Acetylcholine and Glutamate) and Glucose sensors. We discuss the selectivity of these sensors, and study the influence of channel dimensions on their sensitivity. Finally, approaches to increase the spatial and temporal resolution of these transistors are presented.
References:
[1] Kergoat L, Piro B, Simon DT, Pham MC, Noël V, and Berggren M. Adv Mater 26: 5658-5664, 2014.
[2] Khodagholy D, Curto VF, Fraser KJ, Gurfinkel M, Byrne R, Diamond D, Malliaras GG, Benito-Lopez F, and Owens RM. J Mater Chem 22: 4440-4443, 2012.
[3] Bernards DA, Macaya DJ, Nikolou M, DeFranco JA,Takamatsu S, and Malliaras GG. J Mater Chem 18: 116-120, 2008.