Macromolecular Phase Separation in Biology I

Presentations

• Protein condensates as aging Maxwell fluids

  Invited

  March 5, 2020, 11:15 AM – March 5, 2020, 11:51 AM

  Presenters

  • Louise Jawerth

    • Max Planck Institute for the Physics of Complex Systems
    • for the Physics of Complex Systems, Max Planck Institute

  Authors

  • Louise Jawerth

    • Max Planck Institute for the Physics of Complex Systems
    • for the Physics of Complex Systems, Max Planck Institute

  View abstract →

• Surface Fluctuations and Coalescence of Nucleolar Droplets in the Human Cell Nucleus

  ORAL

  March 5, 2020, 11:51 AM – March 5, 2020, 12:03 PM

  Presenters

  • Christina M. Caragine

    • Physics, New York Univ NYU

  Authors

  • Christina M. Caragine

    • Physics, New York Univ NYU

  • Shannon C Haley

    • Physics, New York Univ NYU
    • University of California, Berkeley

  • Alexandra Zidovska

    • Physics, New York Univ NYU
    • New York Univ NYU

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• Phase separation in the nucleus is limited by chromatin mechanics

  ORAL

  March 5, 2020, 12:03 PM – March 5, 2020, 12:15 PM

  Presenters

  • Yaojun Zhang

    • Princeton University

  Authors

  • Yaojun Zhang

    • Princeton University

  • Daniel Lee

    • Princeton University

  • Yigal Meir

    • Ben-Gurion University
    • Physics, Ben-Gurion University

  • Cliff Brangwynne

    • Princeton University
    • Department of Chemical and Biological Engineering, Princeton University; Howard Hughes Medical Institute

  • Ned Wingreen

    • Princeton University
    • Department of Molecular Biology; Lewis-Sigler Institute for Integrative Genomics, Princeton University

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• Subdiffusive Dynamics of Optogenetic Droplets Report on Local Chromatin Mechanics

  ORAL

  March 5, 2020, 12:15 PM – March 5, 2020, 12:27 PM

  Presenters

  • Daniel Lee

    • Lewis-Sigler Institute for Integrative Genomics, Princeton University

  Authors

  • Daniel Lee

    • Lewis-Sigler Institute for Integrative Genomics, Princeton University

  • Shunsuke Shimobayashi

    • Department of Chemical and Biological Engineering, Princeton University

  • Yi-Che Chang

    • Department of Chemical and Biological Engineering, Princeton University

  • Amy R Strom

    • Department of Chemical and Biological Engineering, Princeton University

  • Ned Wingreen

    • Princeton University
    • Department of Molecular Biology; Lewis-Sigler Institute for Integrative Genomics, Princeton University

  • Cliff Brangwynne

    • Princeton University
    • Department of Chemical and Biological Engineering, Princeton University; Howard Hughes Medical Institute

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• Converting Stochastic Assembly into an Assembly Line: Non-Equilibrium Droplet Dynamics Assists Ribosome Formation

  ORAL

  March 5, 2020, 12:27 PM – March 5, 2020, 12:39 PM

  Presenters

  • Tyler Harmon

    • Max Planck Institute for the Physics of Complex Systems

  Authors

  • Tyler Harmon

    • Max Planck Institute for the Physics of Complex Systems

  • Frank Julicher

    • Max-Planck-Institute for the Physics of Complex Systems
    • Max Planck Institute for the Physics of Complex Systems
    • Max Planck Institute for the Physics of Complex Systems, Dresden, Germany

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• Reentrant Liquid Condensation of Ribonucleoprotein–RNA Complexes

  ORAL

  March 5, 2020, 12:39 PM – March 5, 2020, 12:51 PM

  Presenters

  • Muralikrishna Raju

    • Iowa State University

  Authors

  • Muralikrishna Raju

    • Iowa State University

  • Rabia Laghmach

    • Iowa State University

  • Davit Potoyan

    • Iowa State University

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• Size selection of phase-separated liquid droplets in strain-stiffening elastic networks

  ORAL

  March 5, 2020, 12:51 PM – March 5, 2020, 1:03 PM

  Presenters

  • Sheng Mao

    • Princeton University

  Authors

  • Sheng Mao

    • Princeton University

  • Mikko Haataja

    • Princeton University

  • Andrej Kosmrlj

    • Princeton University

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• A hydrodynamic instability drives TPX2 protein droplet formation on microtubules and leads to branching microtubule nucleation

  ORAL

  March 5, 2020, 1:03 PM – March 5, 2020, 1:15 PM

  Presenters

  • Sagar Setru

    • Princeton University

  Authors

  • Sagar Setru

    • Princeton University

  • Bernardo Gouveia

    • Princeton University

  • Raymundo Alfaro-Aco

    • Princeton University

  • Matthew R King

    • Princeton University

  • Howard A Stone

    • Princeton University
    • Department of Mechanical and Aerospace Engineering, Princeton University

  • Joshua Shaevitz

    • Princeton University
    • Physics and the Lewis-Sigler Institute, Princeton University
    • Physics, Princeton University

  • Sabine Petry

    • Princeton University

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• Motif Sequences and Intracellular Phase Separation

  ORAL

  March 5, 2020, 1:15 PM – March 5, 2020, 1:27 PM

  Presenters

  • Benjamin Weiner

    • Princeton University

  Authors

  • Benjamin Weiner

    • Princeton University

  • Yigal Meir

    • Ben-Gurion University
    • Physics, Ben-Gurion University

  • Ned Wingreen

    • Princeton University
    • Department of Molecular Biology; Lewis-Sigler Institute for Integrative Genomics, Princeton University

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• Coupling signaling cascades to membrane criticality

  ORAL

  March 5, 2020, 1:27 PM – March 5, 2020, 1:39 PM

  Presenters

  • Taylor Schaffner

    • Yale University

  Authors

  • Taylor Schaffner

    • Yale University

  • Benjamin B Machta

    • Physics, Yale University
    • Yale University
    • Department of Physics, Yale University

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• Wetting of Critical Membranes by Protein Droplets

  ORAL

  March 5, 2020, 1:39 PM – March 5, 2020, 1:51 PM

  Presenters

  • Mason Rouches

    • Molecular Biophysics and Biochemistry, Yale University

  Authors

  • Mason Rouches

    • Molecular Biophysics and Biochemistry, Yale University

  • Sarah Veatch

    • Biophysics, University of Michigan

  • Benjamin B Machta

    • Physics, Yale University
    • Yale University
    • Department of Physics, Yale University

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• Probing the Dynamics of Optically Induced Protein Droplets with Single-Walled Carbon Nanotubes

  ORAL

  March 5, 2020, 1:51 PM – March 5, 2020, 2:03 PM

  Presenters

  • Hugh Higinbotham

    • Massachusetts Institute of Technology MIT

  Authors

  • Hugh Higinbotham

    • Massachusetts Institute of Technology MIT

  • Sebastian Coupe

    • Massachusetts Institute of Technology MIT

  • Yoon Jung

    • Massachusetts Institute of Technology MIT

  • Nikta Fakhri

    • Massachusetts Institute of Technology MIT
    • MIT
    • Physics, Massachusetts Institute of Technology
    • Massachusetts Institute of Technology

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• Measuring protein concentrations in biomolecular condensates via quantitative phase microscopy

  ORAL

  March 5, 2020, 2:03 PM – March 5, 2020, 2:15 PM

  Presenters

  • Patrick McCall

    • Max Planck Institute for the Physics of Complex Systems
    • Max Planck Institute of Molecular Cell Biology and Genetics; Max Planck Institute for the Physics of Complex Systems; Center for Systems Biology Dresden

  Authors

  • Patrick McCall

    • Max Planck Institute for the Physics of Complex Systems
    • Max Planck Institute of Molecular Cell Biology and Genetics; Max Planck Institute for the Physics of Complex Systems; Center for Systems Biology Dresden

  • Kyoohyun Kim

    • Biotechnology Center, Technische Universität Dresden; Max Planck Institute for the Science of Light

  • Jie Wang

    • Max Planck Institute of Molecular Cell Biology and Genetics

  • Anatol W. Fritsch

    • Max Planck Institute of Molecular Cell Biology and Genetics; Max Planck Institute for the Physics of Complex Systems; Center for Systems Biology Dresden

  • Andrey Poznyakovskiy

    • Max Planck Institute of Molecular Cell Biology and Genetics

  • Benedict Diederich

    • Leibniz Institute of Photonic Technology

  • Moritz Kreysing

    • Max Planck Institute of Molecular Cell Biology and Genetics; Center for Systems Biology Dresden

  • Rainer Heintzmann

    • Leibniz Institute of Photonic Technology; Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich-Schiller-University Jena

  • Jochen Guck

    • Biotechnology Center, Technische Universität Dresden; Max Planck Institute for the Science of Light

  • Simon Alberti

    • Max Planck Institute of Molecular Cell Biology and Genetics; Biotechnology Center, Technische Universität Dresden

  • Jan Brugués

    • Max Planck Institute of Molecular Cell Biology and Genetics; Max Planck Institute for the Physics of Complex Systems; Center for Systems Biology Dresden

  • Anthony Hyman

    • Max Planck Institute for Cell Biology and Genetics
    • Max Planck Institute of Molecular Cell Biology and Genetics
    • Max Planck Institute for Molecular Cell Biology and Genetics

  View abstract →