Design and Control of Finite Conformational Changes in Mechanical Networks
ORAL
Abstract
Conformational changes in physical networks play a crucial role in many systems, enabling error correction in DNA replication, cooperativity in hemoglobin, and mechanical capacities in metamaterials. Important work has begun to delineate the relationship between network structure and instantaneous conformational change. However, these efforts have failed to address finite conformations, which are critical for the successful function of most physical networks. Here we establish a simple framework for the design and control of mechanical spring networks in 2 and 3 dimensions. Specifically, for a set of nodes with arbitrarily specified initial and final positions, we characterize all bipartite networks with zero energy at these positions, demonstrate transitions between these positions, and design multi-stable networks for information storage. Finally, we use hysteresis and bi-stability to design networks demonstrating cooperativity.
*JZK acknowledges support from NIH T32-EB020087, PD: Felix W. Wehrli, and the NSF GRFP No. DGE-1321851. DSB acknowledges support from the John D. and Cather- ine T. MacArthur Foundation, the ISI Foundation, the Alfred P. Sloan Foundation, an NSF CAREER award PHY-1554488, and from the NSF through the University of Pennsylvania MRSEC DMR-1720530.
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Presenters
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Jason Kim
- University of Pennsylvania