Confined ring polymers as a model nucleoid

ORAL

Abstract

The bacterial chromosome is tightly packed in an intracellular space called the nucleoid with its loci linearly and precisely positioned. Here we propose a model nucleoid: a ring polymer confined in a cylindrical space. When the cylinder-ring parameters are chosen properly, our model describes the observed locus distributions of the {\it E. coli} chromosome surprisingly well. Our results illustrate how the geometry and function of the nucleoid are interrelated.

*This work was supported by the collaborative research contract funded by Korea Institute of Science \& Technology Information (KISTI, Korea) and NSERC (Canada).

Authors

  • Bae-Yeun Ha

    • University of Waterloo
  • C. Jeon

    • University of Waterloo
  • J. Kim

    • KAIST, Korea
  • H. Jeong

    • KAIST, Korea
  • S. Jun

    • University of California, San Diego
  • Y. Jung

    • KISTI, Korea