Nanopore Translocation Dynamics of star polymers

ORAL

Abstract

The translocation of polymers through a narrow channel or a nanopore has a significant impact on numerous biological systems and industrial process, examples including rapid DNA sequencing, controlling drug delivery, and designing nanopore sequencing device.We consider the dynamics of flow-induced translocation of star polymers through a nanopore in three dimensions by dissipative particle dynamics approach, focusing on the dependence of the translocation time on the polymer chain length. The scaling of the average translocation time $\tau $ \textit{vs.} the total length $N_{\mbox{tot}} $ of the star polymer with three arms, $\tau \sim N_{\mbox{tot}}^{1.09\pm 0.04}$, is obtained in our simulation. We establish that the overall translocation time, with the translocation probability $P_{i}^{\mbox{trans}} $ and the translocation time $\tau_{i}$ under different translocation paths. We demonstrate that the translocation time $\tau$ of star polymers through the nanopore increases with the increase of the total arm numbers, while $\tau$ decreases with increasing number the forward arms that are initially squeezed into the nanopore. Our findings may provide a valuable guidance for experimental studies on the conformational and dynamics behaviors of star polymer translocation for further applications.

*This work has been supported by NNSFC (Nos. 20874046 and 21074053) and NBRPC (No. 2010CB923303).

Authors

  • Rong Wang

    • Nanjing University, Department of Polymer Science and Engineering, State Key Laboratoryof Coordination Chemistry
  • Zhu Liu

    • Nanjing University, Department of Polymer Science and Engineering, State Key Laboratoryof Coordination Chemistry