Translocation dynamics of a semi-flexible chain through a nano-pore

ORAL

Abstract

We study translocation dynamics of a semi-flexible chain through a nano-pore in two dimensions (2D) using Langevin dynamics simulation. Specifically, we show how the mean first passage time (MFPT) and the probability distribution of the MFPT are both influenced by the bending rigidity of the chain. Furthermore, we monitor the chain conformations both at the cis and the trans sides and relate these results with recent theories and experiments for a translocating chain through a nano-pore.

*Partially supported by NSF-CHEM (AB); Supported by NSF-DMR-0701610 (RA and AL),

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Authors

  • Ramesh Adhikari

    • Florida Atlantic University

  • Andy W.C. Lau

    • Florida Atlantic University

  • Aniket Bhattacharya

    • Department of Physics, University of Central Florida
    • University of Central Florida