How Fast Liposomes Diffuse in the Extracellular Matrix

POSTER

Abstract

Single-particle tracking is used to compare the diffusivity of soft spheres (liposomes) with that of hard spheres of the same size, when they are embedded within gels whose mesh size is smaller than the particle size. The comparison is made in model systems and also in cell extracts of closer biological relevance. In both environments, the diffusivity of liposomes is systematically faster than that of hard spheres.

Authors

  • James Kuo

    • UIUC
    • University of Illinois

  • Bo Wang

    • UIUC
    • University of Illinois

  • Sung Chul Bae

    • UIUC
    • University of Illinois

  • Steve Granick

    • University of Illinois at Urbana-Champaign
    • UIUC