Characterization of Self-Forming Liposomes

POSTER

Abstract

We are currently using Raman spectroscopy to investigate thermodynamic phase transitions of self-forming liposomes, trademarked QuSomes {\texttrademark}. A Renishaw InVia Raman microscope system is used to acquire Raman spectra using a low-power argon ion laser (514.5 nm). A temperature-controlled sample holder is used to vary the temperature between -4 and 110\r{ }C. Spectral indications of phase transitions are seen. Techniques to examine mechanical properties of liposome formation, as well as size distribution and separation, are being developed. Preliminary data will be presented.

Authors

  • Zephyr McCormick

    • Department of Physics, University of Nevada, Reno

  • Rajan Bista

    • Department of Medicine, University of Pittsburgh

  • Aaron Covington

    • Department of Physics, University of Nevada, Reno