Determination of Frank-Oseen parameters in collagen using polarization modulated second harmonic signal.

ORAL

Abstract

A method is presented for determining the Frank-Oseen parameters for the elastic modulus of collagen based on analysis of polarization-modulated second harmonic signal (PM-SHG). The liquid crystal structure of collagen and its associated order parameter, the director field, were characterized in samples of tendon and annulus fibrosus.~ Deformation of the director field caused by controlled stress loading or heating was assessed. Three distinct curvature strains--splay, twist, and bend---were determined, using the PM-SHG data. This optical technique permits highly localized determination of the three major elastic deformations.

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Authors

  • Clayton Bratton

    • University of California, Davis - Physics

  • Karen Reiser

    • University of California, Davis - Neurosurgery

  • Andre Knoesen

    • University of California, Davis - Electrical and Computer Engineering

  • Diego Yankelevich

    • University of California, Davis - Electrical and Computer Engineering

  • Mingshi Wang

    • University of California, Davis - Electrical and Computer Engineering

  • Israel Rocha - Mendoza

    • Cardiff University, Cardiff, Wales - Cardiff School of Biosciences