Cluster structure in urea aqueous solution and it's effect on DNA denature
ORAL
Abstract
The existence of large cluster structure in urea aqueous solution is proved by Small Angle Neutron Scattering (SANS). Our results indicate that urea is a water- structure-breaker, and large urea cluster will be formed when it's concentration is higher than 20 w{\%}. This cluster is very stable, and almost do not change with temperature. The helix-to-coil denaturation transition of DNA was studied with various urea concentrations, to testify the solvent structure influence on this process.
*Joint Laboratory of Polymer Science and Materials, ICCAS, Beijing, China
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