Direct nm-scale observation of lipid membrane fluctuations

ORAL

Abstract

Thermal fluctuation of giant unilamellar phospholipids vesicles(GUVs) was observed by a combination of direct imaging using epifluorescence microscopy and forward laser beam scattering of a laser beam from the vesicle edge. The latter technique, owing to the refractive index mismatch, offers nanometer spatial and microsecond temporal resolution. When nanoparticles adsorb, this changes. We will discuss the changes of membrane rigidity caused by nanoparticles, based on membrane fluctuation data.

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Authors

  • Sung Chul Bae

    • Department of Materials Science and Engineering, University of Illinois
    • Dept of Materials Science and Engineering, Univ of Illinois-Urbana Champaign

  • Yan Yu

    • Department of Materials Science and Engineering, University of Illinois

  • Stephen Anthony

    • Department of Chemistry, University of Illinois
    • Dept of Chemistry, Univ of Illinois-Urbana Champaign

  • Steve Granick

    • Department of Materials Science and Engineering, University of Illinois
    • Dept of Materials Science and Engineering, Physics, Chemistry and Chemical Engineering, Univ of Illinois-Urbana Champaign