Single Molecule Dynamics of Polymers Confined in Nanochannels

COFFEE_KLATCH  · Invited

Abstract

I will review our work on the conformational dynamics of polymers, in particular genomic length DNA molecules, in nanochannels whose diameter is less than the persistence length of the polymer. I will discuss how these dynamics give some insight into how nanochannels can be used for the next generation of single molecule mapping/sequencing techniques.

*Supported by the NSF funded NBTC of Cornell University, NIH, DARA and US Genomics

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Authors

  • Robert Austin

    • Princeton University
    • Princeton Universiy Dept. of Physics
    • Department of Physics, Princeton University