Unprecedented conservation law of evolution and Methuselah age.

Extensive data establish that mortality in evolutionary unprecedented protected populations is predominantly universal for humans, flies, nematodes, yeast. The law which is preserved in evolution of species as biologically remote as humans and yeast is a conservation law of evolution. Conservation laws are well known in physics, but conservation law of evolution is unprecedented. It describes mortality dynamics of live animals which strongly interact with changing environment. Yet the law reduces only to current population characteristics, and does not depend on any variables specific for environment or interaction with it. This must be related to homeostasis which is specific for live systems. The law implies selection which, in contrast to species specific natural selection, proceeds via universal stepwise evolutionary rungs. The law suggests that universal mortality is a disposable evolutionary byproduct, and directed genetic and/or biological changes may yield healthy and vital Methuselah lifespan. This is consistent with recent experiments, and may be related to genes, which were beneficial for non-universal longevity in the wild, but became detrimental in evolutionary unprecedented protected conditions. Universality implies that single cell yeast may provide a master key to the mechanism of mortality and adaptation in all animals.