Removal of Chronic Intravascular Blood Clots using Liquid Plasma

ORAL

Abstract

An electrical embolectomy device for removing chronic intravascular blood clots using liquid plasma under saline environment was demonstrated. We employed a proxy experimental blood clot model of deep vein thrombosis (DVT) and actual equine blood clot. Thermal damage to contiguous tissue and the collagen denaturing via the plasma irradiation were investigated by histological analysis using birefringence of the tissue and verified by FT-IR spectroscopic study, respectively, which showed the high removal rate up to 2 mm per minute at room temperature and small thermal damage less than 200 $\mu$m.

Authors

  • Jae-Chul Jung

    • Colorado State University
  • Myeong Yeol Choi

    • Colorado State University
  • Il Gyo Koo

    • Colorado State University
  • Zengqi Yu

    • Colorado State University
  • George J. Collins

    • Colorado State University