Ultra-sensitive human breath analysis via cavity-enhanced frequency comb spectroscopy

ORAL

Abstract

Molecules present in exhaled human breath yield a wealth of information about the physiological and metabolic status of a human body. Similar to how blood tests can be used as a disease diagnostics tool, breath analysis has attracted much attention since it enables measurements to be performed in a non-invasive and potentially real-time manner. Several molecules present in the breath have been identified as biomarkers and correlated with specific diseases, such as nitrogen monoxide with asthma, acetone with diabetes, and ammonia with renal failure. In this talk, we will report how we apply cavity-enhanced mid-infrared frequency comb spectroscopy to provide simultaneous detection of multiple breath biomarkers at exceptionally high detection sensitivity levels.

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Presenters

  • Qizhong Liang

    • University of Colorado, Boulder
    • JILA, NIST, and University of Colorado, Boulder
    • JILA, NIST, and University of Colorado at Boulder

Authors

  • Qizhong Liang

    • University of Colorado, Boulder
    • JILA, NIST, and University of Colorado, Boulder
    • JILA, NIST, and University of Colorado at Boulder

  • Jutta Toscano

    • University of Colorado, Boulder
    • JILA, NIST, and University of Colorado, Boulder
    • JILA, NIST, and University of Colorado at Boulder

  • Ya-Chu Chan

    • JILA, NIST, and University of Colorado, Boulder
    • JILA, NIST, and University of Colorado at Boulder

  • P. Bryan Changala

    • JILA, NIST, and University of Colorado, Boulder
    • JILA, NIST, and University of Colorado at Boulder

  • David J Nesbitt

    • JILA, NIST, and University of Colorado, Boulder
    • JILA, NIST, and University of Colorado at Boulder

  • Jun Ye

    • JILA and University of Colorado Boulder
    • JILA, University of Colorado, Boulder
    • University of Colorado, Boulder
    • JILA, NIST, and University of Colorado Boulder
    • JILA, University of Colorado Boulder
    • JILA, University of Colorado and National Institute of Standards and Technology, and Department of Physics, University of Colorado, Boulder, Colorado 80309, USA
    • JILA, National Institute of Standards and Technology and Department of Physics, University of Colorado, Boulder, Colorado 80309, USA
    • JILA, NIST, and Department of Physics, University of Colorado, Boulder
    • JILA, NIST, and University of Colorado, Boulder
    • JILA, NIST, and University of Colorado at Boulder