Development of an NV-diamond magnetometer for application in neuroscience

POSTER

Abstract

Magnetic field imaging based on optically detected magnetic resonances (ODMR) in NV-diamond offers an unmatched combination of sensitivity, resolution and field-of-view. For certain biological applications NV-diamond imaging is particularly useful; in contrast to traditional fluorescent markers, NV-diamond imaging is label-free and does not suffer from bleaching. In addition, the solid-state nature of NV-diamond imaging allows for various fast modulation techniques to be employed to increase the signal-to-noise ratio. Here we present results demonstrating the magnetic detection of action potentials from single neurons in multiple types of invertebrate organisms. Furthermore, we lay out a path forward for imaging of the magnetic field associated with neuronal activity with the goal of application to mammalian neurons.

Authors

  • John Barry

    • Harvard University
    • Harvard-Smithsonian Center for Astrophysics, Department of Physics, Harvard Unviersity

  • Jennifer Schloss

    • MIT

  • Matthew Turner

    • Harvard University
    • Department of Physics, Harvard University

  • David Glenn

    • Harvard University

  • Ronald Walsworth

    • Harvard CfA
    • Harvard-Smithsonian Center for Astrophysics
    • Harvard-Smithsonian Center for Astrophysics and Harvard University
    • Harvard University
    • Harvard-Smithsonian Center for Astrophysics, Department of Physics, Harvard Unviersity