New Algorithm for Small Volume, Fast, Accurate Blood Analysis (FABA) for Blood Diagnostics via Hand-Held XRF on Drops Rapidly Solidified into Uniform Thin Films

Comprehensive Blood Diagnostics (BD) uses mLs of blood, and hours to days for results. BD leads to a 74{\%} rate of a serious illness, Hospital-Acquired-Anemia, in chronically ill patients. In this work, a new, fast, portable, comprehensive Small Volume BD device, InnovaStrip [1], solidifies drops into Homogeneous Thin Solid Films (HTSF). Using micro-Ls, HTSFs yield electrolytes and metals levels to $+$/- 10{\%}, the medical standard, using Ion Beam Analysis and X-ray Fluorescence (XRF). Therefore, a new, Fast , Accurate Blood Analysis (FABA) [1] algorithm has to interface InnovaStrip with PCs/smartphones. FABA is developed initially for a low cost, hand-held XRF of HTSF App, called Fast Hand-Held Analysis for XRF(FHAX). Present XRF analysis software such as Spectra.Elements do not measure trace elements to $+$/- 10{\%} because curve fitting focuses large XRF signals for all elements, not small trace element signals [1]. FABA extracts actual Riemann sum of X-ray counts for each selected trace element. FABA yields fast (\textless 5 min), accurate BD to $+$/-10{\%} of blood electrolytes and metals, in mg/dL not atomic {\%} , via built-in HTSF of calibration solutions in InnovaStrip. [1] Balasooriya, Herbots, \textit{et al.} Pat. Pend. (2020)